Related topics: cancer cells

Climate-associated genetic switches found in plants

Genetic variants that can act as switches directing structural changes in the RNA molecules that code for proteins in plants have been experimentally validated in plants for the first time. The changes to RNA structure can ...

Self-regulation of an enzyme with critical cellular functions

The lab of Kathy Gould, Louise B. McGavock Professor and professor of cell and developmental biology, used a multi-disciplinary approach that included structural biology, biochemistry, and molecular biology to investigate ...

Researchers uncover genetic 'bridge' to leukemia progression

For cells to thrive, a complex network of three-dimensional structures assembles to read, copy and produce the genetic materials (DNA) needed for cellular function. Understanding how these structures form, and what happens ...

Effect of small polyanions on retroviruses

A retrovirus is a virus that inserts a copy of its genome into the DNA of a host cell that it invades, thus changing that cell's genome. Once inside the host cell's cytoplasm, the virus uses its reverse transcriptase enzyme ...

Better in pairs: Proteins can help one another bind to DNA

Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other's binding to DNA in fission yeast. They found that Atf1 and Rst2 help each other stably ...

Solving a long-standing biological search problem

How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university ...

Untwisting DNA reveals new force that shapes genomes

Advances in microscopy have enabled researchers to picture loops of DNA strands for the first time. The images reveal how the human genome organizes itself in three-dimensional space at much higher resolution than previously ...

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