Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.
Molecular & Computational biology
Nov 22, 2021
0
848
Research at Indiana University has identified a genetic mechanism that is likely to drive mutations that can lead to cancer.
Biotechnology
Feb 1, 2016
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1014
In spore-forming bacteria, chromosomal locations of genes can couple the DNA replication cycle to critical, once-in-a-lifetime decisions about whether to reproduce or form spores. The new finding by Rice University bioengineers ...
Cell & Microbiology
Jul 9, 2015
8
784
(Phys.org) —For the first time, an elusive step in the process of human DNA replication has been demystified by scientists at Penn State University. According to senior author Stephen J. Benkovic, an Evan Pugh Professor ...
Cell & Microbiology
Apr 1, 2013
3
0
For the first time, researchers have been able to use cryo-electron microscopy, to reveal the detailed structure of the common herpes virus.
Biochemistry
Jul 5, 2018
0
112
DNA replication is a tightly regulated process that ensures the precise duplication of the genome during cell proliferation. Replication origins determine where replication starts on the genome and regulate the whole genome ...
Molecular & Computational biology
Dec 27, 2019
0
221
Researchers at the University of Wisconsin–Madison have described the way an enzyme and proteins interact to maintain the protective caps, called telomeres, at the end of chromosomes, a new insight into how a human cell ...
Cell & Microbiology
Aug 1, 2022
0
192
At the same time that a cell's DNA gets duplicated, a third of it gets super-compacted into repetitive clumps called heterochromatin. This dense packing serves to repress or "silence" the DNA sequences within -- which could ...
Cell & Microbiology
Oct 16, 2011
0
0
It may come as a bit of a surprise to learn that bacteria have an immune system - in their case to fight off invasive viruses called phages. And like any immune system - from single-celled to human - the first challenge of ...
Cell & Microbiology
Apr 13, 2015
1
47
Just like how letters are strung together to form words, our DNA is also strung together by letters to encode proteins. The genetic alphabet contains only 4 natural letters - A, C, G and T, which hold the blueprint for the ...
Biotechnology
Oct 26, 2017
1
111
