Our genomic DNA is continuously damaged by endogenous factors such as reactive oxygen species, and also by environmental factors such as ultraviolet light, radiation, and chemicals. Failure to repair damaged DNA may induce ...
Molecular & Computational biology
Jun 12, 2023
0
31
DNA is well known as the blueprint of life, necessary for an organism to facilitate living processes. DNA can be damaged by various factors such as radical metabolites, radiation, and some toxic chemicals. As DNA is a molecule ...
Cell & Microbiology
May 18, 2023
0
6
A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.
Cell & Microbiology
May 16, 2023
0
100
Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working ...
Biotechnology
May 11, 2023
0
279
Our DNA is constantly exposed to damaging factors that can lead to aging and age-related diseases such as cancer. PARP1 is an important enzyme that facilitates the response to DNA damage by attaching chemical groups called ...
Cell & Microbiology
Apr 28, 2023
0
558
The DNA molecules in our cells can be damaged by various extrinsic and intrinsic factors called genotoxic stressors; persistent and unchecked damage can lead to developing diseases like cancer. Fortunately, our cells don't ...
Cell & Microbiology
Apr 26, 2023
0
8
Male beetles face a trade-off between competing with other males for mating opportunities and repairing damage to their sperm DNA, according to a study published April 4 in the open access journal PLOS Biology by Mareike ...
Plants & Animals
Apr 4, 2023
0
119
A new study shows exactly how the gene BRCA2, linked to susceptibility to breast and ovarian cancer, functions to repair damaged DNA. By studying BRCA2 at the level of single molecules, researchers at the University of California, ...
Cell & Microbiology
Apr 3, 2023
0
3
Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide. Looking to contribute a solution to this growing problem, ...
Cell & Microbiology
Mar 31, 2023
0
75
A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered. They also successfully inhibited ...
Cell & Microbiology
Mar 23, 2023
0
196
