LMU researchers have determined the structure of a key enzyme complex that is involved in DNA repair, and traced the cycle of conformational changes that it undergoes while performing its biochemical function.
Molecular & Computational biology
Sep 4, 2019
0
7
Very little was known till now about DNA repair by homologous recombination, which is fundamental for human health. Now an ETH research group has for the first time isolated and studied all the key proteins involved in this ...
Cell & Microbiology
Aug 19, 2019
0
50
A team of Vanderbilt investigators has discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.
Biotechnology
Jul 29, 2019
0
26
Different African killifish species vary extensively in their lifespans—from just a few months to several years. Scientists from the Max Planck Institute for Biology of Ageing in Cologne investigated how different lifespans ...
Evolution
Jul 3, 2019
0
1
In the time it takes for an Amazon Prime delivery to arrive, cells damaged by chemotherapy can almost completely fix their most important DNA. That is the case in the livers of mice at least, according to a new study.
Biochemistry
Jul 1, 2019
0
0
UV light damages the DNA of skin cells, which can lead to skin cancer. But this process is counteracted by DNA repair machinery, acting as a molecular sunscreen. It has been unclear, however, how repair proteins work on DNA ...
Molecular & Computational biology
May 30, 2019
0
82
Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the ...
Molecular & Computational biology
May 21, 2019
0
171
Explorers have dreamt for centuries of a Fountain of Youth, with healing waters that rejuvenate the old and extend life indefinitely.
Biotechnology
Apr 22, 2019
0
853
Scientists at UMass Medical School have developed a strategy for editing and repairing a particular type of genetic mutation associated with microduplications using CRISPR-Cas9 and a seldom-used DNA repair pathway. Described ...
Biotechnology
Apr 4, 2019
0
164
As David Cortez, Ph.D., tells the story of his research team's latest discovery, he shakes his head in disbelief.
Cell & Microbiology
Mar 1, 2019
0
33
