A mutational timer is built into the chemistry of DNA

If you had to copy billions of letters from one sheet of paper to another, you'd probably make a few mistakes. So it might not come as a surprise that when DNA makes a copy of its three-billion-base genetic code, it can slip ...

Genes in Space-3 successfully identifies unknown microbes in space

Being able to identify microbes in real time aboard the International Space Station, without having to send them back to Earth for identification first, would be revolutionary for the world of microbiology and space exploration. ...

Chemists use modified DNA nucleotides to create new materials

DNA evolved to store genetic information, but in principle this special, chain-like molecule can also be adapted to make new materials. Chemists at The Scripps Research Institute (TSRI) have now published an important demonstration ...

Shining a spotlight on the machinery of life

Researchers from the Max Planck Institute for the Science of Light in Erlangen have developed a technique for directly observing how enzymes and other biomolecules go about their work, with potentially significant medical ...

Crystal structure reveals details of nonstandard RNA transcription

High-resolution crystal structure reveals a new pathway for RNA during a nontraditional form of transcription—the process by which RNA is produced from a DNA template. Caught during the act of reiterative transcription, ...

How head-on collisions of DNA protein machines stop replication

A new study describes how head-on collisions between protein machines on chromosomes can disrupt DNA replication and boost the rate of gene mutations that help bacteria survive hostile environments, resist antibiotics, and ...

Ultrasensitive DNA quantification by light scattering

Traces of biomolecules such as DNA can be detected with a new "dynamic" technique based on the observation of association and dissociation events of gold nanoparticles. If the desired DNA sequence is present, it can reversibly ...

Refined DNA tool tracks native and invasive fish

Rather than conduct an aquatic roll call with nets to know which fish reside in a particular body of water, scientists can now use DNA fragments suspended in water to catalog invasive or native species.

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