Current sequencing techniques lack the sensitivity to detect rare gene mutations in a pool of cells, which is particularly important, for example, in early cancer detection. Now, scientists at KAUST have developed an approach, ...
Biotechnology
Aug 26, 2020
0
14
The extinction of prehistoric megafauna like the woolly mammoth, cave lion, and woolly rhinoceros at the end of the last ice age has often been attributed to the spread of early humans across the globe. Although overhunting ...
Archaeology
Aug 13, 2020
6
1842
All life is subject to evolution in the form of mutations that change the DNA sequence of an organism's offspring, after which natural selection allows the 'fittest' mutants to survive and pass on their genes to future generations. ...
Evolution
Aug 10, 2020
0
204
Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy. But CRISPR-Cas9 also has spawned other potentially powerful DNA manipulation tools that could help fix genetic ...
Biotechnology
Jul 30, 2020
0
425
Base editors, which enable production of highly efficient targeted point mutations in genomic DNA without causing double-stranded DNA breaks, hold great promise for gene therapy in human disease and trait improvement in crop ...
Biotechnology
Jul 27, 2020
0
5
New genome-editing technologies developed by researchers in J. Keith Joung's laboratory at the Massachusetts General Hospital (MGH) have the potential to help understand disease-associated genetic mutations that are based ...
Cell & Microbiology
Jul 23, 2020
0
345
One could say that mitochondria, the energy-producing organelles inside every human cell, dance to their own beat. After all, they have their own genome—a set of DNA-containing chromosomes—completely separate from the ...
Plants & Animals
Jul 9, 2020
0
67
Scientists can now precisely edit the genes inside mitochondria, the tiny energy factories inside of cells.
Biotechnology
Jul 8, 2020
1
294
Epigenetic regulation of gene expression is associated with switching between chromatin states characterized by distinct histone modifications.
Cell & Microbiology
Jun 30, 2020
0
120
Whilst most organisms try to stop their DNA from mutating, scientists from the UK and China have discovered that a common fungus found on bread actively mutates its own DNA as a way of fighting virus-like infections.
Biotechnology
Jun 22, 2020
0
112
