Related topics: dna sequences · protein

Innate immunity—to operate, insert dimers

The presence of DNA in mammalian cell cytoplasm triggers an immune response by binding to a dimeric enzyme, which inserts between DNA double helices to form the 'rungs' of a ladder-like structure, as an LMU team has now shown.

Chromosome motor discovery supports DNA loop extrusion

It is one of the great mysteries in biology: How does a cell neatly distribute its replicated DNA between two daughter cells? For more than a century, we have known that DNA in the cell is comparable to a plate of spaghetti—a ...

Research shows how DNA molecules cross nanopores

Research presented in a new paper co-authored by Northwestern University associate professor of mechanical engineering Sandip Ghosal sheds new light on how polymers cross tiny pores ten thousand times smaller than a human ...

How the genome sets its functional micro-architecture

The genes that are involved in the development of the fetus are activated in different tissues and at different times. Their expression is carefully regulated by so-called "enhancer sequences", which are often located far ...

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