Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.
Cell & Microbiology
Sep 28, 2020
0
6
Some of the genetic differences that have arisen between domesticated chickens and their wild ancestors, the red junglefowl, are linked to epigenetic changes, according to a new study published in Nature Ecology & Evolution. ...
Plants & Animals
Sep 21, 2020
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213
A team of researchers from New Jersey Institute of Technology (NJIT) and Children's Hospital of Philadelphia (CHOP) have developed an algorithm through machine learning that helps predict sites of DNA methylation—a process ...
Biotechnology
Aug 6, 2020
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196
DNA methylation performs an essential function in mammalian ontogeny. It is also known that abnormalities in this process cause the development of cancers such as leukemia.
Cell & Microbiology
Jul 21, 2020
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5
There are about 75 different types of cells in the human brain. What makes them all different? Researchers at Baylor College of Medicine have developed a new set of computational tools to help answer this question. Although ...
Biotechnology
Jul 1, 2020
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139
Scientists at EMBL Rome unveil the mechanism behind the most studied epigenetic modification.
Biotechnology
Jun 11, 2020
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110
While the first genome-wide DNA methylation map in mammalian cells was established over 10 years ago, such maps only provide snapshots and do not inform about the actual dynamics of this epigenetic mark. Researchers from ...
Biotechnology
Jun 2, 2020
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16
Although all cells in an organism have the same genetic information, not all perform the same function, being as not all of them have the same active genes. Part of these differences in gene activity is due to DNA methylation, ...
Biotechnology
May 19, 2020
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2
Why do normal cells turn into cancer cells? One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation. The joint research groups of The Institute of Medical Science, ...
Molecular & Computational biology
Mar 17, 2020
0
6
When the machinery that guides the transition of stem cells to somatic cells doesn't shut down properly, cells can become cancerous. Identifying the mechanisms that impede those processes would offer scientists a target for ...
Cell & Microbiology
Feb 11, 2020
0
111
