Genomes are routinely subjected to DNA damage. But most cells have DNA repair systems that enforce genome stability and, ideally, prevent diseases like cancer. The trouble gets serious when these systems break down. When ...
Molecular & Computational biology
Sep 16, 2020
0
44
Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers at Karlsruhe Institute of Technology (KIT) have demonstrated that DNA damage may also occur ...
Biochemistry
Sep 14, 2020
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595
A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan. The international team's ...
Biotechnology
Aug 21, 2020
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202
A collaborative project between the Center for Genome Integrity, within the Institute for Basic Science (IBS, South Korea), and the Dundee School of Life Sciences, the EMBL's European Bioinformatics Institute (EMBL-EBI), ...
Cell & Microbiology
Jun 8, 2020
0
7
The gene p53 is extremely important in cell biology and, hence, the world of cell replacement therapy. Its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the "tumor suppressor ...
Cell & Microbiology
Jun 1, 2020
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1
Researchers at Karolinska Institutet have developed a new sequencing method that makes it possible to map how DNA is spatially organized in the cell nucleus—revealing which genomic regions are at higher risk of mutation ...
Cell & Microbiology
May 26, 2020
0
24
DNA damage in general and DNA strand breaks in particular occur every day in all cells of the human body. This is due to internal influences such as free radicals, which are produced during inflammatory processes and cellular ...
Biotechnology
May 1, 2020
0
20
Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases. Their findings, published in the journal ...
Cell & Microbiology
Mar 25, 2020
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7
In collaboration with Stanford University, a working group from MedUni Vienna's Division of Cell and Developmental Biology, led by Mark Wossidlo, has identified the role of a factor involved in early embryonic development. ...
Cell & Microbiology
Mar 23, 2020
1
320
It's estimated that there are approximately 80,000 industrial chemicals currently in use, in products such as clothing, cleaning solutions, carpets, and furniture. For the vast majority of these chemicals, scientists have ...
Biochemistry
Dec 17, 2019
0
26
