An international collaboration between Osaka University and the Friedrich Miescher Institute for Biomedical Research (FMI) in Switzerland is investigating the repair process of a serious form of DNA damage that can lead to ...
Biotechnology
Jan 19, 2017
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4
Earlier work from the laboratory of Susan Gasser had noted changes in the physical behavior of chromatin when it incurred DNA damage: loci bearing double-strand breaks showed enhanced movement, becoming highly dynamic. Furthermore, ...
Cell & Microbiology
Jan 10, 2017
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12
New research has revealed the function of a widely shared enzyme component, the Zf-GRF domain, as a critical molecular tool necessary for manipulating DNA during repair processes.
Cell & Microbiology
Jan 7, 2017
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26
A research team led by scientists at the Icahn School of Medicine at Mount Sinai (ISMMS) has solved the three-dimensional structure of a key protein that helps damaged cellular DNA repair itself. Investigators say that knowing ...
Cell & Microbiology
Oct 25, 2016
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44
The genetic information of every cell is encoded in the sequence of the DNA double helix. Double strand breaks in the DNA, which can be induced by radiation, are a dangerous threat to the cells, and if not properly repaired ...
Cell & Microbiology
Sep 27, 2016
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7
New research has identified crucial biological sensors that determine seed longevity and control germination. ATM and ATR proteins sense DNA damage in seeds and are essential factors that help plants retain correct genetic ...
Ecology
Sep 26, 2016
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9
Double-stranded breaks in DNA can be detected with several technologies. Doing so in plants is exceptionally difficult, but GUIDE-Seq shows promise in new studies.
Biotechnology
Sep 22, 2016
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256
Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus, promoting intact DNA ...
Cell & Microbiology
Sep 12, 2016
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7
Scientists from the University of Sussex have discovered how an enzyme, known as PARP3, helps to accelerate the repair of DNA.
Cell & Microbiology
Sep 5, 2016
2
69
A UT Dallas physicist has developed a novel technology that not only sheds light on basic cell biology, but also could aid in the development of more effective cancer treatments or early diagnosis of disease.
General Physics
Aug 25, 2016
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