Dynamic DNA helps ward off gene damage, study reveals
Researchers have identified properties in DNA's protective structure that could transform the way scientists think about the human genome.
Researchers have identified properties in DNA's protective structure that could transform the way scientists think about the human genome.
Cell & Microbiology
Jun 15, 2017
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All cells are confronted with DNA damage, for example by exposure of the skin to UV rays, chemical byproducts of nerve cells consuming sugar, or immune cells destroying bacteria. If these DNA lesions are not - or badly - ...
Cell & Microbiology
Jun 13, 2017
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183
We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.
Cell & Microbiology
May 11, 2017
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Scientists at the Francis Crick Institute have made a surprising discovery about the Vaccinia virus, a large DNA virus belonging to the pox family that was used as the vaccine to eradicate smallpox.
Cell & Microbiology
May 3, 2017
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197
Genetic studies in mice have identified a molecular mechanism crucial to maintaining egg cells in a dormant state to ensure female fertility. This work by A*STAR identifies a potential method to prevent infertility when the ...
Cell & Microbiology
Apr 5, 2017
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DNA repair is essential for cell vitality, cell survival, and cancer prevention, yet cells' ability to patch up damaged DNA declines with age for reasons not fully understood.
Cell & Microbiology
Mar 24, 2017
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New Danish research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. The results may eventually help to improve the treatment of certain types of cancer, as the DNA repair complex provides ...
Biochemistry
Mar 21, 2017
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It's well known that when the DNA in a cell is damaged, the cell responds by activating specific genes that help defend the integrity of its genome. But less well studied is the fact that the cell actually shuts down the ...
Cell & Microbiology
Feb 17, 2017
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Day in and day out, in our bodies, the DNA in cells is damaged for a variety of reasons, and thus intercellular DNA-repair systems are fundamental to the maintenance of life. Now scientists from the UNC School of Medicine ...
Cell & Microbiology
Feb 7, 2017
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A team of researchers from the biology department at TU Darmstadt has discovered that the processes for repairing DNA damage are far more complex than previously assumed. The ends of breaks in the double helix are not just ...
Cell & Microbiology
Feb 2, 2017
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9