Crumpled graphene makes ultra-sensitive cancer DNA detector

Graphene-based biosensors could usher in an era of liquid biopsy, detecting DNA cancer markers circulating in a patient's blood or serum. But current designs need a lot of DNA. In a new study, crumpling graphene makes it ...

Protecting DNA origami for anti-cancer drug delivery

Scientists have designed and synthesized chains of molecules with a precise sequence and length to efficiently protect 3-D DNA nanostructures from structural degradation under a variety of biomedically relevant conditions. ...

'Optical tweezers' help in quest for better cancer treatments

Stem cells involved in replenishing human tissues and blood depend on an enzyme known as telomerase to continue working throughout our lives. When telomerase malfunctions, it can lead to both cancer and premature aging conditions. ...

Condensins mutually interact to fold DNA into a zigzag structure

DNA in a cell is comparable to tangled spaghetti strands on a plate. To be able to divide DNA neatly between the two daughter cells during cell division, the cell organises this tangle into tightly packed chromosomes. A protein ...