Dengue, a mosquito-borne tropical disease, remains a threat not just in Singapore but in Southeast Asia and beyond. Just this year, Singapore had more than 30,000 cases. Using advanced techniques in cryogenic electron microscopy, ...
Molecular & Computational biology
Dec 7, 2022
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94
Tiny droplets in cells can accelerate the accumulation of protein deposits in diseases such as Alzheimer's and Parkinson's disease, but they can also hinder this accumulation. While they will worsen the accumulation if the ...
Biochemistry
Dec 5, 2022
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232
Scientists at Scripps Research have reported success in initial tests of a new, nanotech-based strategy against autoimmune diseases.
Bio & Medicine
Dec 1, 2022
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341
Researchers in the lab of Harvard Medical School structural biologist Hao Wu have deciphered the step-by-step assembly of a molecular complex that's crucial for fighting off infections but can also give rise to myriad diseases ...
Biochemistry
Nov 29, 2022
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20
Ancient, dormant sequences in the genome impact embryonic development in unexpected ways. The mammalian genome contains retroviral sequences that are in an undead but mostly "harmless" state. An international research team ...
Cell & Microbiology
Nov 23, 2022
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32
Nucleic acid therapies involving DNA or RNA have significant potential to treat genetic disorders, infectious diseases, and cancer; however, research suggests that less than 1% of injected nucleic acid doses reach target ...
Bio & Medicine
Nov 23, 2022
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21
Regulating the fluid balance in cells is vital in all living things. When insufficient water is being transported via the cell membrane, cells can use their aquaporins—also known as water channels—that open and close ...
Cell & Microbiology
Nov 21, 2022
0
361
Water—which makes up the majority of every cell in the body—plays a key role in how proteins, including those associated with Parkinson's disease, fold, misfold, or clump together, according to a new study.
Biochemistry
Nov 15, 2022
0
44
The widely used gene scissor (CRISPR/Cas) can modify the genetic content in cells to study the molecular roles of genes and has gained great clinical relevance in gene therapy to treat genetic diseases. A new study performed ...
Biotechnology
Nov 14, 2022
0
108
Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer. However, immune checkpoint inhibition therapy is only effective in 20%–30% ...
Bio & Medicine
Oct 31, 2022
0
5
