Sestrin makes fruit flies live longer

Reduced food intake, known as dietary restriction, leads to a longer lifespan in many animals and can improve health in humans. However, the molecular mechanisms underlying the positive effects of dietary restriction are ...

What we've learned about the nucleolus since you left school

The size of a cell's nucleolus may reveal how long that cell, or even the organism that cell belongs to, will live. Over the past few years, researchers have been piecing together an unexpected link between aging and an organelle ...

Dietary restriction and life span in male and hermaphrodite worms

An organism's lifespan is known to be affected by its sex and diet, but where these two factors overlap biologically is not well understood. Researchers in Japan looked for clues in worms—C. elegans—that have two sexes: ...

Dietary restriction can improve learning in worms

Dietary restriction - the reduction of a specific nutrient or total dietary intake without triggering malnutrition—increases longevity and improves learning, but are these processes regulated separately? A new study publishing ...

Dieting causes epigenetic changes during ageing

Reduced food consumption extends the lifespan of many organisms, including primates. The biology behind how this is achieved, however, is not yet fully understood. Researchers at the Max Planck Institute for Biology of Ageing ...

Dietary restriction gives fruit flies a rhythm for a long life

Dietary restriction enhances the expression of the circadian clock genes in the peripheral tissue of fruit flies, according to research from the Kapahi lab at the Buck Institute. Publishing in Cell Metabolism, the researchers ...