Machine-learning model helps determine protein structures

Cryo-electron microscopy (cryo-EM) allows scientists to produce high-resolution, three-dimensional images of tiny molecules such as proteins. This technique works best for imaging proteins that exist in only one conformation, ...

World record resolution in cryo electron microscopy

Holger Stark from the Max Planck Institute for Biophysical Chemistry in Göttingen and his team have broken a crucial resolution barrier in cryo electron microscopy. For the first time, his group succeeded in observing individual ...

New algorithm sharpens focus of world's most powerful microscopes

We've all seen that moment in a cop TV show where a detective is reviewing grainy, low-resolution security footage, spots a person of interest on the tape, and nonchalantly asks a CSI technician to "enhance that." A few keyboard ...

Tiny protein motor fuels bacterial movement

There are billions of bacteria around us and in our bodies, most of which are harmless or even helpful. But some bacteria such as E. coli and salmonella can cause infections. The ability to swim can help bacteria to seek ...

Biochemists trap and visualize an enzyme as it becomes active

How do you capture a cellular process that transpires in the blink of an eye? Biochemists at MIT have devised a way to trap and visualize a vital enzyme at the moment it becomes active—informing drug development and revealing ...

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