CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases. However, there is a last-mile problem—these tools need to be effectively ...
Biotechnology
9 hours ago
0
178
A team of scientists has created a three-dimensional map showing how a small molecule with anticancer properties—called spliceostatin—can promote the killing of cancer cells. This fundamental discovery could ultimately ...
Cell & Microbiology
May 04, 2022
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135
We live in a world made and run by RNA, the equally important sibling of the genetic molecule DNA. In fact, evolutionary biologists hypothesize that RNA existed and self-replicated even before the appearance of DNA and the ...
Bio & Medicine
May 02, 2022
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1882
G protein-coupled receptors (GPCRs) play a crucial role in cell signal transduction and comprise the largest drug target protein family. Despite recent breakthroughs in structural and pharmacological studies of these receptors, ...
Cell & Microbiology
Apr 20, 2022
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65
Tetrahymena, a tiny single celled-organism, turns out to be hiding a surprising secret: it's doing respiration—using oxygen to generate cellular energy—differently from other organisms such as plants, animals or yeasts. ...
Cell & Microbiology
Mar 31, 2022
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397
In humans, virtually every cell stores fat. However, patients with a rare condition called congenital lipodystrophy, which is often diagnosed in childhood, cannot properly store fat, which accumulates in the body's organs ...
Cell & Microbiology
Feb 25, 2022
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83
The vast majority of biological processes rely on proteins to carry out various jobs in all living cells, including neurons, which transmit information throughout the nervous system.
Cell & Microbiology
Feb 03, 2022
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36
Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or feces of Mastomys rats. Even though many people who become infected with Lassa ...
Cell & Microbiology
Dec 02, 2021
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27
The intricate functions of cellular processes have mystified scientists for decades. But with the help of tools like cryogenic electron microscopy (Cryo-EM), researchers at Penn State College of Medicine are starting to see ...
Biotechnology
Dec 01, 2021
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108
The proteins that belong to the HAT family are essential for life as they transport amino acids across the cell membrane. Although the members of this family are practically identical, some transport certain amino acids and ...
Cell & Microbiology
Nov 29, 2021
0
98
