Cryo-electron microscopy opens a door to fight Epstein-Barr

The Epstein-Barr virus is one of the most widespread human viruses. Part of the herpesvirus family, it causes glandular fever (infectious mononucleosis), cancer and autoimmune diseases. At present, there is no treatment for ...

How to construct a protein factory

Cells consist of a multitude of molecular structures, some of them exhibiting a staggering complexity. Ribosomes, the protein factories of the cell, belong to the biggest and most sophisticated complexes and are made up of ...

New software brings lower-resolution cryo-EM maps into focus

Cryo-electron microscopy is now the most popular method for determining protein structures, which helps researchers develop drugs for different kinds of ailments. Over the last several decades, it has replaced X-ray crystallography ...

A new mechanism for accessing damaged DNA

UV light damages the DNA of skin cells, which can lead to skin cancer. But this process is counteracted by DNA repair machinery, acting as a molecular sunscreen. It has been unclear, however, how repair proteins work on DNA ...

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