Building the machinery that makes proteins

All of the proteins necessary for life are made by giant molecular machines called ribosomes. A ribosome, in turn, is built from proteins and ribosomal RNAs stitched together with immaculate precision.

The nanoscopic structure that locks up our genes

For decades, scientists could only speculate about the shape of heterochromatin, a type of chromatin that consists of tightly packed DNA and proteins. Recently, however, researchers from the Okinawa Institute of Science and ...

The spliceosome—now available in high definition

UCLA researchers have solved the high-resolution structure of a massive cellular machine, the spliceosome, filling the last major gap in our understanding of the RNA splicing process that was previously unclear.

Discovery of a potential therapeutic target to combat trypanosomes

Yaser Hashem's team at the Laboratoire Architecture et Réactivité de l'ARN at CNRS's has discovered a new potential therapeutic target - located in the ribosome - to combat trypanosomes parasites. Using cryo-electron microscopy, ...

Lab technology brings Nobel-winning cryo-EM into sharper focus

Pioneering work by scientists at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) played a key role in the 2017 Nobel Prize in chemistry, awarded today, honoring the development of cryo-electron ...

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