Over the past 30 years, progress in early detection and treatment of cancer has helped reduce the overall death rate by more than 30%. Pancreatic cancer, however, has remained difficult to treat. Only 1 in 9 people survive ...
Bio & Medicine
Sep 13, 2022
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199
ETH researchers are shedding light on what can happen when cells exceed their normal size and become senescent. The new findings could help to optimize cancer therapies.
Cell & Microbiology
Nov 17, 2023
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80
Treatment of cancer is a long-term process because remnants of living cancer cells often evolve into aggressive forms and become untreatable. Hence, treatment plans often involve multiple drug combinations and/or radiation ...
Biochemistry
Sep 8, 2022
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74
Drug-resistant superbugs pose a huge threat to human health. Currently, colistin is regarded as the last-line antimicrobial against extensively drug resistant (XDR) bacterial infections caused by pathogens, such as Salmonella, ...
Cell & Microbiology
Apr 14, 2022
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48
St. Jude Children's Research Hospital scientists have identified a new therapeutic strategy that enhanced cancer immunotherapy, slowed tumor growth and extended the lives of mice with cancer. The research appears today in ...
Cell & Microbiology
Dec 12, 2019
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370
Physicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation.
Bio & Medicine
Jun 17, 2020
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7
Drug-coated iron nanowires that can be guided to the site of a tumor using an external magnetic field before activating a three-step cancer-killing mechanism could provide an effective option for cancer therapy.
Bio & Medicine
Jan 28, 2020
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10
NUS scientists in collaboration with researchers from Norvatis have discovered two genetic markers in Plasmodium falciparum, the deadliest malaria parasite that can cause it to develop resistance against a new antimalarial ...
Cell & Microbiology
Jan 3, 2018
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76
By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with ...
Diseases, Conditions, Syndromes
Aug 11, 2016
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6
Combining nanodrug-based chemotherapy and cryoablation provides an effective strategy to eliminate cancer stem-like cells (CSCs) the root of cancer resistance and metastasis, which will help to improve the safety and efficacy ...
Bio & Medicine
Mar 13, 2014
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0
In contemporary usage, the expression combination therapy most often refers to the simultaneous administration of two or more medications to treat a single disease, but the expression is also used when other types of therapy are used at the same time.
Conditions treated with combination therapy include tuberculosis, leprosy, cancer, malaria, and HIV/AIDS.
Combination therapy may seem costlier than monotherapy in the short term but causes significant savings: lower treatment failure rate, lower case-fatality ratios, slower development of resistance and consequently, less money needed for the development of new drugs.
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