A new study challenges the conventional wisdom surrounding genome stability within closely related organisms and sheds new light on the mechanisms underlying extensive genome size variation.
Cell & Microbiology
Aug 8, 2023
0
9
Every modern mammal, from a platypus to a blue whale, is descended from a common ancestor that lived about 180 million years ago. We don't know a great deal about this animal, but the organization of its genome has now been ...
Plants & Animals
Sep 27, 2022
7
4935
Evolutionary chromosomal changes may take a million years in nature, but researchers are now reporting a novel technique enabling programmable chromosome fusion that has successfully produced mice with genetic changes that ...
Biotechnology
Aug 25, 2022
0
420
A study led by scientists at the UAB and conducted with mice models reveals how chromosomal reorganizations alter the genome's three-dimensional organization in germ cells. The study, published in Nature Communications, opens ...
Biotechnology
May 20, 2021
0
13
From cancer treatment to sunlight, radiation and toxins can severely damage DNA in both harmful and healthy cells. While the body has evolved to efficiently treat and restore damaged cells, the mechanisms that allow this ...
Molecular & Computational biology
Apr 15, 2021
0
150
Alterations to chromosomes are considered important in speciation (the process by which new species are formed). This is because several chromosomal rearrangements can make the genome of a few individuals in a population ...
Evolution
May 26, 2020
0
2
Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism. Now, researchers from Japan have identified mechanisms that choose between alternate pathways of DNA repair to ...
Evolution
Apr 30, 2020
0
17
Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes ...
Cell & Microbiology
Jan 24, 2019
0
5
A team of researchers from Denmark, Malaysia, France and the U.K. has conducted a genome assembly of the donkey to learn more about its evolutionary history. In their paper published on the open access site Science Advances, ...
The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division. When they mutate ...
Cell & Microbiology
Mar 1, 2018
0
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