Device could help detect signs of extraterrestrial life

Although Earth is uniquely situated in the solar system to support creatures that call it home, different forms of life could have once existed, or might still exist, on other planets. But finding traces of past or current ...

Estimating bisphenol exposures in the Australian population

Once found in bottles, food containers, cash register receipts and electronics, bisphenol A (BPA) has been phased out of many products because of health concerns and government regulations. As a result, the production and ...

A new understanding of protein movement

Many of the most promising medicines under development are proteins, often antibodies, to help patients fight disease. These proteins must be purified as part of the manufacturing process—a task that can be tricky and result ...

Medieval blue dye's molecular structure identified

A team of researchers affiliated with several institutions in Portugal has identified the molecular structure of folium, a blue watercolor dye used by medieval artists and book publishers. In their paper published in the ...

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Chromatography

Chromatography (from Greek χρῶμα chroma "color" and γράφειν graphein "to write") is the collective term for a set of laboratory techniques for the separation of mixtures. The mixture is dissolved in a fluid called the "mobile phase", which carries it through a structure holding another material called the "stationary phase". The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus changing the separation.

Chromatography may be preparative or analytical. The purpose of preparative chromatography is to separate the components of a mixture for further use (and is thus a form of purification). Analytical chromatography is done normally with smaller amounts of material and is for measuring the relative proportions of analytes in a mixture. The two are not mutually exclusive.

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