'Acidic patch' regulates access to genetic information

Chromatin remodelers—protein machines that pack and unpack chromatin, the tightly wound DNA-protein complex in cell nuclei—are essential and powerful regulators for critical cellular processes, such as replication, recombination ...

A new energy source within the cells

All our cells require the small molecule, ATP, generated in the mitochondria to cover the energy required for cell metabolism, dynamics and growth. To a lower extent and particularly in cancer cells, ATP can also be generated ...

Discovered: How to unlock inaccessible genes

An international team of biologists has discovered how specialized enzymes remodel the extremely condensed genetic material in the nucleus of cells in order to control which genes can be used. The discovery will be published ...

BRIT1 allows DNA repair teams access to damaged sites

Like a mechanic popping the hood of a car to get at a faulty engine, a tumor-suppressing protein allows cellular repair mechanisms to pounce on damaged DNA by overcoming a barrier to DNA access.