Discovery of naturally chiral surfaces for safer pharmaceuticals

In the 1960s, the sedative thalidomide was widely popular as one of the only non-barbiturate, over-the-counter sleep-aids on the market. When doctors started noticing that it also helped alleviate morning sickness in pregnant ...

Fluorine enables separation-free 'chiral chromatographic analysis'

Researchers from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences recently developed a new platform for rapid chiral analysis, producing chromatogram-like output without the need for separation. ...

Researchers access both enantiomers by varying reaction time

Homochirality is a fundamental feature of all living organism. It is well known that a pair of enantiomers of chiral drug molecules, whose structures have a non-superimposable mirror-image relationship to each other, will ...

Electrochemical reaction powers new drug discoveries

A Cornell-led collaboration is flipping the switch on traditional synthetic chemistry by using electricity to drive a new chemical reaction that previously stumped chemists who rely on conventional methods.

A fresh twist in chiral topology

The concept of chirality is well-established in science: when an object cannot be superimposed on its mirror image, both the object and its mirror image are called chiral. In the drug industry, for instance, more than 50% ...

Chemists are able to induce uniform chirality

Chirality is a fundamental property of many organic molecules and means that chemical compounds can appear in not only one form, but in two mirror-image forms as well. Chemists at Martin Luther University Halle-Wittenberg ...

Using corkscrew lasers to separate chiral molecules

Many of the molecular building blocks of life have two versions that are mirror images of one another, known as enantiomers. Although seemingly identical, the two enantiomers can have completely different chemical behaviour—a ...

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