Protein chaperone takes its job seriously

For proteins, this would be the equivalent of the red-carpet treatment: each protein belonging to the complex machinery of ribosomes—components of the cell that produce proteins—has its own chaperone to guide it to the ...

Research sheds light on workings of anti-cancer drug

(PhysOrg.com) -- The copper sequestering drug tetrathiomolybdate (TM) has been shown in studies to be effective in the treatment of Wilson disease, a disease caused by an overload of copper, and certain metastatic cancers. ...

Microscopic collisions help proteins stay healthy

Studies at The University of Texas Health Science Center at San Antonio are providing basic new understanding about "heat shock proteins," also called "chaperone proteins." These proteins, first identified in cells subjected ...

Chaperones for climate protection

(PhysOrg.com) -- The World Climate Conference recently took place. Reports about carbon dioxide levels, rising temperatures and melting glaciers appear daily. Scientists from the Max Planck Institute (MPI) of Biochemistry ...

Study reveals dynamics of crucial immune system proteins

Of the many marvels of the human immune system, the processing of antigens by the class I proteins of the major histocompatability complex (MHC-I) is among the most mind-boggling. Exactly how these proteins carry out their ...

Unraveling one of prion disease's deadly secrets

A molecular biologist at the University of Massachusetts Amherst who has for decades studied the nightmarish group of fatal diseases caused by prions—chronic wasting disease in deer, mad cow in cattle and its human analog—credits ...

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