Centriole instability might contribute to some cases of microcephaly

Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole ...

Super-resolution microscopy reveals a twist inside of cells

If you want to understand the underlying mechanisms of cellular motility and division, then the centriole is the organelle of interest. Each cell has a pair of centrioles which help to segregate chromosomes during cell division. ...

A scaffold at the center of our cellular skeleton

All animal cells have an organelle called a centrosome, which is essential to the organization of their cell skeleton. The centrosome plays fundamental roles, especially during cell division, where it allows equal sharing ...

How cells learn to 'count'

One of the wonders of cell biology is its symmetry. Mammalian cells have one nucleus and one cell membrane, and most humans have 23 pairs of chromosomes. Trillions of mammalian cells achieve this uniformity—but some consistently ...

Scientists gain new insights into the mechanisms of cell division

Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists led by Alexander Dammermann at the Max Perutz ...

Progress in super-resolution microscopy

Going deeper and deeper into cells with the microscope; imaging the nucleus and other structures more and more accurately; getting the most detailed views of cellular multi-protein complexes: All of these are goals pursued ...

Algorithms to locate centrioles in the cell

Investigators from the Neurodegenerative Diseases Research Group at the University of Extremadura are studying signaling mediated by a pathway known as planar cell polarity (PCP), which regulates the coordinated orientation ...

Super-resolution microscopy builds multicolor 3-D from 2-D

Super-resolution microscopy is a technique that allows researchers to see beyond the diffraction limit of light. The technique has garnered increasing interest, especially since its developers won the Nobel Prize in Chemistry ...

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