Hereditary neurodegeneration linked to ADP-ribose modification

Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...

How did early primordial cells evolve?

Four billion years ago, soon after the planet cooled enough for life to begin, primordial cells may have replicated and divided without protein machinery or cell walls, relying instead on just a flimsy lipid membrane. New ...

Gene network illuminates stress, mutation and adaptation responses

For much of her professional life, Dr. Susan Rosenberg has studied the puzzling response of bacteria to stress and the mutations that result. In the current issue of the journal Science, she puts together the pieces of that ...

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