Related topics: protein

When dangerous toxins teach fundamental biology

"What our work shows is how a complex in the center of the cell, the ER-Golgi interaction region, controls plasma membrane cholesterol, which is essential for many cellular functions, if not essential for multicellular life," ...

Single-cell sequencing

When studying any kind of population—people or cells—averaging is a useful, if flawed, form of measurement. According to the US Census Bureau, the average American household size in 2010 was 2.59. Of course, there are ...

Caltech modeling feat sheds light on protein channel's function

Chemists at the California Institute of Technology have managed, for the first time, to simulate the biological function of a channel called the Sec translocon, which allows specific proteins to pass through membranes. The ...

New role for the JNK protein

Put simply, a tumor is the result of out-of-control cell growth. To assure that the cell cycle - the cell's process of duplicating itself to make more cells - goes smoothly, a large network of proteins tells other proteins ...

A question of gene silencing

When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do ...

Study reveals why certain drug combinations backfire

Combination drug therapy has become a staple for treating many infections. For instance, doctors treat extensively drug resistant forms of tuberculosis with one drug that breaks down the pathogen's protective barriers and ...

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