SARS-CoV-2 uses sugars to invade human cells

Sugars found on the surface of human cells influence COVID-19 infection, according to a University of Alberta-led study that is one of the first to observe this relationship and suggests that cells in the brain might be particularly ...

Frizzleds are dynamic, molecular machines

Maria Kowalski-Jahn and Hannes Schihada, two postdocs in the Schulte laboratory, have used a novel technology of fluorescently labeling receptors with a minimally invasive technique and detecting structural rearrangements ...

How density governs receptor activation on immune cells

Scientists from within the Antibody and Vaccine Group at the University of Southampton have gained novel insights into how an important class of immune receptors called tumor necrosis factor receptors (TNFR) are activated.

Uncovering the structure and gating mechanism of a7 protein

UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes. The work, published online today in Cell, could eventually ...

Plant immunity requires two-step detection of invaders

Plants perceive pathogens and activate immunity using two very different types of receptors. Receptors at the cell surface detect pathogen-derived molecules that accumulate outside plant cells, activating pattern-triggered ...

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