Bioengineers can tailor the genomes of cells to create "cellular therapies" that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch ...
Cell & Microbiology
Aug 14, 2023
0
1
Wnt signaling is a well-known mode of cell-to-cell communication in multicellular biological organisms. It involves the secretion of small Wnt glycoproteins, by signaling cells, that bind to receptor proteins in the membrane ...
Molecular & Computational biology
Aug 3, 2023
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66
As life propagated across Earth in the form of the widest variety of single-celled organisms, sometime between 3.5 and 1 billion years ago one such organism managed an evolutionary coup: Instead of devouring and digesting ...
Cell & Microbiology
Jul 28, 2023
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35
Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks—damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling ...
Biochemistry
Jul 27, 2023
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61
The same message can be interpreted differently by different individuals; also true among cells. This is shown by researchers at Linköping University who studied cell communication through Wnt signaling, which plays a decisive ...
Cell & Microbiology
Jul 19, 2023
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1
Is it possible that in most measurements in the field of life sciences, important interactions remain hidden inside the cell or at the cell surface? This question has puzzled the team of laser- and bio-physicist Prof. Dr. ...
Cell & Microbiology
Jul 14, 2023
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13
A cochlear signal, the exact role of which has been unclear since its discovery around 70 years ago, probably gives the brain information on whether the ear is functioning normally or not. This is the conclusion of a study ...
Cell & Microbiology
Jul 4, 2023
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77
A research group at the Graduate School of Science, Nagoya University in Japan has used artificial intelligence to determine that piezo, a channel that receives mechanical stimuli, plays a role in controlling the mating posture ...
Plants & Animals
Jun 27, 2023
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14
Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane. One such receptor involved ...
Biochemistry
Jun 8, 2023
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168
University of Queensland researchers have shown for the first time that some of the world's most painful ant stings target nerves, like snake and scorpion venom. This research is published in Nature Communications.
Plants & Animals
Jun 6, 2023
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