Scientists open up new world for biologics—inside the cell

The vast majority of top-selling drugs are biologics—also known as proteins. Proteins are used today to treat many debilitating diseases, including arthritis, Crohn's disease, and several forms of cancer. They have helped ...

The protein with the starting gun

Whether dormant bacteria begin to reproduce is no accidence. Rather, they are simply waiting for a clear signal from a single protein in the cell interior. ETH researchers have now deciphered the molecular mechanisms behind ...

How receptors for medicines work inside cells

G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.

Electron microscopy reveals how vitamin A enters the cell

Using a new, lightning-fast camera paired with an electron microscope, Columbia University Medical Center (CUMC) scientists have captured images of one of the smallest proteins in our cells to be "seen" with a microscope.

Building protocells from inorganic nanoparticles

(Phys.org) —Researchers at the University of Bristol have led a new enquiry into how extremely small particles of silica (sand) can be used to design and construct artificial protocells in the laboratory. The work is described ...

Living cells behave like fluid-filled sponges

Animal cells behave like fluid-filled sponges in response to being mechanically deformed according to new research published today in Nature Materials.

Thermal conductivity of argon at high pressures and temperatures

Diamond anvil cells (DACs) are used routinely in laboratories to apply extreme pressure to materials, recreating conditions that normally only occur deep in planetary interiors or during certain industrial manufacturing techniques. ...

Cell membrane is patterned like a patchwork quilt

(Phys.org) -- As the interface between the cell and its environment, the cell membrane, which consists of fats and proteins, fulfils a variety of vital functions. Scientists at the Max Planck Institute of Biochemistry in ...

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