Scientists engineer synthetic DNA to study 'architect' genes

Researchers at New York University have created artificial Hox genes—which plan and direct where cells go to develop tissues or organs—using new synthetic DNA technology and genomic engineering in stem cells.

Biomolecular condensates within cells found to have structure

Every cell contains millions of protein molecules. Some of them have the ability to phase-separate to form non-membrane-bound compartments, called biomolecular condensates, inside a cell. It has long been assumed that there ...

How to find marker genes in cell clusters

Which genes are specific for a certain cell type, i.e., "mark" their identity? With the increasing size of datasets nowadays, answering this question is often challenging. Often, marker genes are simply genes that have been ...

Swirling bacteria mimic Van Gogh's 'The Starry Night'

Scientists have discovered a way to transform millions of predatory bacteria into swirling flash mobs reminiscent of painter Vincent Van Gogh's "The Starry Night" as the unexpected result of experiments on a genetic circuit ...

Uncovering molecular mechanisms behind cell signaling

A study led by Northwestern Medicine investigators has identified the molecular mechanisms within protein complexes that promote cell-to-cell adhesion and communication, according to findings published in the Proceedings ...

How density governs receptor activation on immune cells

Scientists from within the Antibody and Vaccine Group at the University of Southampton have gained novel insights into how an important class of immune receptors called tumor necrosis factor receptors (TNFR) are activated.

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