Mutant prions help cells foil harmful protein misfolding

Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists ...

Proteins find their way with address label and guide

Most newly produced proteins in a cell need to be transported to the proper place before they can be put to work. For proteins to find their way, they have a built-in signal linked to them, a kind of address label. Moreover, ...

Scientists test commonly used antibodies

If a strand of your DNA was stretched out completely, it would be more than six feet long. It's hard to imagine that it can fit inside the nucleus of one of your cells, but that's exactly how it works.

Protein complex key in avoiding DNA repair mistakes, cancer

As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.

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