Related topics: stem cells · cells · arthritis · osteoarthritis

Nanoparticle injections may be future of osteoarthritis treatment

Osteoarthritis is a debilitating condition that affects at least 27 million people in the United States, and at least 12 percent of osteoarthritis cases stem from earlier injuries. Over-the-counter painkillers, such as anti-inflammatory ...

Long-sought fossil mammal with transitional middle ear found

Paleontologists from the American Museum of Natural History and the Chinese Academy of Sciences announce the discovery of Liaoconodon hui, a complete fossil mammal from the Mesozoic found in China that includes the long-sought ...

Some sauropods really did hold their long necks high

(PhysOrg.com) -- A new study suggests the long necks of sauropod dinosaurs really were held high, in spite of theories suggesting they were more likely to keep their necks low because of the very high blood pressure resulting ...

Capturing living cells in micro pyramids

A field full of pyramids, but on a micro scale. Each of the pyramids hides a living cell. Thanks to 3D micro- and nano scale fabrication, promising new applications can be found. One of them is applying the micro pyramids ...

Growing cartilage -- no easy task

Northwestern University researchers are the first to design a bioactive nanomaterial that promotes the growth of new cartilage in vivo and without the use of expensive growth factors. Minimally invasive, the therapy activates ...

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Cartilage

Cartilage is a type of dense connective tissue existing within many joints. It is composed of specialized cells called chondrocytes that produce a large amount of extracellular matrix composed of collagen fibers, abundant ground substance rich in proteoglycan, and elastin fibers. Cartilage is classified in three types, elastic cartilage, hyaline cartilage and fibrocartilage, which differ in the relative amounts of these three main components.

Cartilage is found in many areas in the body, including the articular surface of the bones, the rib cage, the ear, the nose, the bronchial tubes and the intervertebral discs. Its mechanical properties are intermediate between bone and dense connective tissue like tendon.

Unlike other connective tissues, cartilage does not contain blood vessels. The chondrocytes are fed by diffusion, helped by the pumping action generated by compression of the articular cartilage or flexion of the elastic cartilage. Thus, compared to other connective tissues, cartilage grows and repairs more slowly.

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