A research group has unearthed how zinc transporter complexes regulate zinc ion (Zn2+) concentrations in different areas of the Golgi apparatus and revealed that this mechanism finely tunes the chaperone protein ERp44.
Cell & Microbiology
May 29, 2023
0
42
Calcium homeostasis, involving the flow of calcium ions within cells, is essential for cell signaling and function. Importantly, calcium enters the cellular powerplants known as mitochondria, where it fine tunes energy production. ...
Cell & Microbiology
May 10, 2023
0
51
Senescence (the process of growing old) drives the onset and severity of multiple aging-associated diseases and frailty. As a result, there has been an increased interest in mechanistic studies and the search for compounds ...
Cell & Microbiology
Apr 17, 2023
0
22
A team of researchers has developed an electronic biosensor based on DNA aptamers that can detect biomarkers in whole blood samples without the addition of reagents. As the team explains in the journal Angewandte Chemie International ...
Biochemistry
Apr 6, 2023
0
33
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have discovered a mechanism involving ribosomes which helps the heart toggle between a 'regular maintenance mode' for day-to-day function and an 'energy-boost ...
Cell & Microbiology
Mar 7, 2023
0
43
Obese fruit flies are the experimental subjects in a Nature Communications study of the causes of muscle function decline due to obesity. In humans, skeletal muscle plays a crucial role in metabolism, and muscle dysfunction ...
Plants & Animals
Mar 4, 2023
0
10
From pandas to sea lions to tigers, hundreds of wildlife species across the globe are contaminated by potentially harmful "forever chemicals", according to a review of hundreds of peer-reviewed studies.
Environment
Feb 23, 2023
1
105
Policymakers looking to address food systems challenges have access to new analysis and online tools to show the role aquatic foods can play in tackling nutrient deficiencies and cardiovascular disease as well as reducing ...
Environment
Feb 22, 2023
0
12
Women are often underrepresented in cardiac clinical trials—yet they are at least at equally high risk of death due to cardiovascular disease, and at higher risk of developing drug-induced heart complications compared to ...
Evolution
Feb 14, 2023
0
3
Significantly higher arsenic and uranium concentrations in public drinking water have been linked to communities with higher proportions of Hispanic/Latino, American Indian/Alaskan Native, and non-Hispanic Black residents, ...
Environment
Dec 14, 2022
0
87
Cardiovascular disease or cardiovascular diseases refers to the class of diseases that involve the heart or blood vessels (arteries and veins). While the term technically refers to any disease that affects the cardiovascular system (as used in MeSH), it is usually used to refer to those related to atherosclerosis (arterial disease). These conditions have similar causes, mechanisms, and treatments. In practice, cardiovascular disease is treated by cardiologists, thoracic surgeons, vascular surgeons, neurologists, and interventional radiologists, depending on the organ system that is being treated. There is considerable overlap in the specialties, and it is common for certain procedures to be performed by different types of specialists in the same hospital.
Most countries face high and increasing rates of cardiovascular disease. Each year, heart disease kills more Americans than cancer..
It is the number one cause of death and disability in the United States and most European countries (data available through 2005). A large histological study (PDAY) showed vascular injury accumulates from adolescence, making primary prevention efforts necessary from childhood.
By the time that heart problems are detected, the underlying cause (atherosclerosis) is usually quite advanced, having progressed for decades. There is therefore increased emphasis on preventing atherosclerosis by modifying risk factors, such as healthy eating, exercise and avoidance of smoking.
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