Enzyme 'atlas' helps researchers decipher cellular pathways

One of the most important classes of human enzymes are protein kinases—signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction in these cellular pathways ...

Using nanopores to detect epigenetic changes faster

Changes known as epigenetic modifications play an important role in cancer development. Being able to analyze them quickly and reliably could contribute significantly to the further development of personalized therapy. A ...

New cryo-EM images shed light on Wnt signaling

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported ...

Emerging vaccine nanotechnology

In this new article publication from Acta Pharmaceutica Sinica B, researchers discuss emerging vaccine nanotechnology.

From rare soil microbe, a new antibiotic candidate

Demand for new kinds of antibiotics is surging, as drug-resistant and emerging infections are becoming an increasingly serious global health threat. Researchers are racing to reexamine certain microbes that serve as one of ...

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