Turning silenced cancer genes back into fighters

Working with human colon cancer cells and mice, researchers led by experts at the Johns Hopkins Kimmel Cancer Center say they have successfully blocked the activity of portions of a protein known as UHRF1 and restored the ...

New electron microscopy technique limits membrane destruction

Membrane proteins play an important role in many biological processes. Studies suggest they're targeted by more than 50% of all modern medicinal drugs. Unfortunately for researchers, determining their structures has been ...

A better way to measure cell survival

Measuring the toxic effects of chemical compounds on different types of cells is critical for developing cancer drugs, which must be able to kill their target cells. Analyzing cell survival is also an important task in fields ...

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