The path(way) less traveled in DNA double-strand break repair

BRCA1, a protein that is well-known for its role in hereditary breast cancer, is an important part of the cellular system that repairs double-strand DNA breaks. Now, researchers from Japan have discovered a new way in which ...

Study sheds light on mechanism of liposome accumulation in tumors

Dmitri Simberg, Ph.D., associate professor in the University of Colorado Skaggs School of Pharmacy, has released the results of a study of the effectiveness of different types of fluorescent labels used to monitor the accumulation ...

The importance of DNA compaction in tissue formation

Scientists led by Dr. Salvador Aznar-Benitah, head of the Stem Cells and Cancer laboratory at IRB Barcelona, have described the alterations that occur during mammary gland formation when heterochromatin (the part of DNA that ...

First detailed look at crucial enzyme advances cancer research

In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type ...

Breast cancer-on-a-chip for testing immunotherapy drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called 'checkpoint proteins.' These ...

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