A team of researchers at the Sloan Kettering Institute working with a group at the American Museum of Natural History has found evidence of a change in human DNA after diverging from other primates that has made humans more ...
The initials BRCA2 may be best known for a gene associated with many cases of breast cancer, and the protein encoded by the BRCA2 gene is critical to repairing breaks in DNA.
Molecular & Computational biology
Aug 13, 2021
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Damage to DNA is the basic cause of cancer. As you read this, many of your cells are producing new DNA, and some of that DNA will contain errors in its sequence, as the cell makes small mistakes in production.
Biotechnology
Mar 4, 2021
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Scientists have taken pictures of the BRCA2 protein for the first time, showing how it works to repair damaged DNA.
Cell & Microbiology
Oct 5, 2014
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For the first time, researchers at the University of California, Davis, have watched single strands of DNA being prepped for repair. The research, published this week in the journal Nature, has implications for understanding ...
Cell & Microbiology
Oct 29, 2012
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(PhysOrg.com) -- A new study from UC Davis shows how, like a conjuring trick with interlocking rings, two interlocked pieces of DNA are separated after DNA is copied or repaired. The finding was published online Oct. 10 in ...
Cell & Microbiology
Oct 11, 2010
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Scientists at the University of North Carolina at Chapel Hill were among co-authors of a study that described the first isolation and purification of the BRCA2 protein which is produced by a gene whose loss greatly increases ...
Cell & Microbiology
Sep 15, 2010
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(PhysOrg.com) -- A key phase in the repair process of damaged human DNA has been observed and visually recorded by a team of researchers at the University of California, Davis. The recordings provide new information about ...
Jan 29, 2009
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More reference expression data
BRCA2 (Breast Cancer Type 2 susceptibility protein) is a protein that in humans is encoded by the BRCA2 gene. BRCA2 belongs to the tumor suppressor gene family and the protein encoded by this gene is involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double strand breaks.
The BRCA2 gene is located on the long (q) arm of chromosome 13 at position 12.3 (13q12.3), from base pair 31,787,616 to base pair 31,871,804.
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