As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these events in a long protein chain that can be imaged using ...
Cell & Microbiology
Jan 2, 2023
0
490
After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain ...
Cell & Microbiology
Dec 22, 2022
0
25
Water—which makes up the majority of every cell in the body—plays a key role in how proteins, including those associated with Parkinson's disease, fold, misfold, or clump together, according to a new study.
Biochemistry
Nov 15, 2022
0
44
Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest ...
Biotechnology
Oct 27, 2022
0
39
Professor Hiroki Ueda, Assistant Professor Daisuke Tone, Lecturer Koji Ode, and Qianhui Zhang (4th-year graduate student at the time) at the University of Tokyo showed that CaMKIIβ, a predominant protein kinase expressed ...
Molecular & Computational biology
Oct 26, 2022
0
7
Neurodegenerative diseases like Alzheimer's, Parkinson's or Huntington's disease are characterized by the deposition of protein clumps, so-called protein aggregates, in the brains of patients. Even though disease-relevant ...
Biochemistry
Oct 21, 2022
0
127
Fluorescence imaging of biological samples stands to benefit greatly by a RIKEN discovery of a fluorescent protein derived from a Japanese jellyfish that maintains its brightness even when illuminated by strong light.
Biotechnology
Sep 30, 2022
0
39
With a long history of coevolution and coadaptation with humans, dogs have developed exquisite and complex heterospecific social and cognitive capabilities. Thus, the domestic dog offers a unique opportunity to understand ...
Cell & Microbiology
Jul 13, 2022
0
16
City College of New York associate professor of physics Ronald Koder and his team at the Koder Lab are advancing the field of molecular detection by developing the first proteins that can detect a deadly nerve agent called ...
Biochemistry
Jul 6, 2022
1
90
It is now possible to deliver therapeutics based on short interfering RNAs to hepatocytes; however, new delivery solutions are necessary to target additional organs. In a new report now published in Nature Biotechnology, ...
