Controlling carbs and fat: Learning from the fruit fly

Incretins are hormones secreted by intestinal cells that regulate pancreatic insulin and glucagon to control sugar metabolism in mammals. Although counterparts of insulin and glucagon have been identified in invertebrates, ...

Boost for mouse genetic analysis

To understand what role an individual gene plays, biologists have, for 100 years, been using a trick of nature: While in principle, the genome in all cells of an organism is the same, mutations arise in individual cells. ...

New brain sensor offers answers about Alzheimer's

Scientists at the University of Virginia School of Medicine have developed a tool to monitor communications within the brain in a way never before possible, and it has already offered an explanation for why Alzheimer's drugs ...

A groundbreaking genetic screening tool for human organoids

Many of the fundamental principles in biology and essentially all pathways regulating development were identified in so-called genetics screens. Originally pioneered in the fruit fly Drosophila and the nematode C. elegans, ...

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