Spectrin proteins spring into action to restore nucleus

When you lift weights, carry heavy boxes, or engage in physical activity, the cells in your body stretch and deform to accommodate your movements. But how do your cells recover, or return to their original state, once you ...

Anti-malaria drugs: Potential new target identified

A newly described protein could be an effective target for combatting drug-resistant malaria parasites. The protein, the transcription factor PfAP2-I, regulates a number of genes involved with the parasite's invasion of red ...

A method to improve in vitro tests

Before new nanoparticles or other nanomedicines can be injected into the human body, a whole series of tests must be conducted in the laboratory, then in living cells, and in the end on humans. But often the results obtained ...

Detailed view of a molecular toxin transporter

Transport proteins in the cells of our body protect us from particular toxins. Researchers at ETH Zurich and the University of Basel have now determined the high-resolution three-dimensional structure of a major human transport ...

Taking a closer look at genetic switches in cancer

Many things go wrong in cells during the development of cancer. At the heart of the chaos are often genetic switches that control the production of new cells. In a particularly aggressive form of leukemia, called acute myeloid ...

Better and cheaper healthcare with dry blood samples

Dried blood on filter paper stored for future diagnostic purposes – considerably easier than the present-day, resource-consuming method using frozen blood samples in plastic tubes. In a new study, Uppsala researchers have ...

Programmed proteins might help prevent malaria

Despite decades of malaria research, the disease still afflicts hundreds of millions and kills around half a million people each year - most of them children in tropical regions. Part of the problem is that the malaria parasite ...

Big data approach to predict protein structure

Nothing works without proteins in the body, they are the molecular all-rounders in our cells. If they do not work properly, severe diseases, such as Alzheimer's, may result. To develop methods to repair malfunctioning proteins, ...

Operation of ancient biological clock uncovered

A team of Dutch and German researchers has discovered the operation of one of the oldest biological clocks in the world, which is crucial for life on earth as we know it. The researchers applied a new combination of cutting-edge ...

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