Hematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function – and defective regulation of protein production is common in certain types of aggressive human blood cancers. ...
Cell & Microbiology
Apr 6, 2018
0
4
Scientists often talk about cell fate and commitment in terms of mechanisms that control gene expression (transcription factors, chromatin remodeling, etc.). But by studying Diamond-Blackfan anemia (DBA), rare genetic blood ...
Cell & Microbiology
Mar 19, 2018
0
22
Certain white blood cells protect us from bacteria by engulfing them. A research team headed by Prof Dr. Lars Leichert, head of the research group Microbial Biochemistry, Prof Dr. Konstanze Winklhofer from the Department ...
Cell & Microbiology
Mar 6, 2018
0
12
Could tumours help us explain the explosion of life of Earth? Scientists have typically explained the period of history when large animal species became much more diverse very quickly as the result of the planet's rising ...
Earth Sciences
Jan 23, 2018
0
24
Scientists at The Scripps Research Institute (TSRI) have solved the mystery of the structure of Piezo1, a member of a family of proteins that convert physical stimuli such as touch or blood flow into chemical signals. The ...
Cell & Microbiology
Dec 21, 2017
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343
An international team of researchers has identified a cause for chronic bad breath (halitosis), with the help of gene knockout mice from the UC Davis Mouse Biology Program. The results are published Dec. 18 in the journal ...
Biotechnology
Dec 19, 2017
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91
Glycans are essential to virtually every biological process in the body. These complex structures—composed of interlocking sugar molecules—adorn the surfaces of cells in fuzzy profusion. Glycans are a crucial part of ...
Biochemistry
Dec 18, 2017
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37
A team led by scientists at Van Andel Research Institute (VARI) has revealed for the first time the atomic-level structure of a promising drug target for conditions such as stroke and traumatic brain injury.
Biochemistry
Dec 6, 2017
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155
When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins ...
Bio & Medicine
Dec 6, 2017
0
66
In our bodies, proteins carry out almost all essential processes, and protein malfunction causes many diseases. To study the function of a protein, researchers remove it from the cell and subsequently analyze the consequences. ...
Cell & Microbiology
Nov 16, 2017
0
66
