More efficient and longer lasting glucose-responsive insulin that eliminates the need for people with type 1 diabetes to measure their glucose levels could be a step closer thanks to a Monash University-led project.
Bio & Medicine
Mar 14, 2023
0
72
Nearly a century after insulin was discovered, an international team of researchers including University of Utah Health scientists report that they have developed the world's smallest, fully functional version of the hormone, ...
Molecular & Computational biology
Jun 1, 2020
0
359
Scientists have created a non-invasive, adhesive patch, which promises the measurement of glucose levels through the skin without a finger-prick blood test, potentially removing the need for millions of diabetics to frequently ...
Bio & Medicine
Apr 9, 2018
0
2229
Brian Otis gingerly holds what looks like a typical contact lens on his index finger. Look closer. Sandwiched in this lens are two twinkling glitter-specks loaded with tens of thousands of miniaturized transistors. It's ringed ...
Hi Tech & Innovation
Jan 17, 2014
2
0
(PhysOrg.com) -- People with type I diabetes must prick their fingers several times a day to test their blood sugar level. Though the pain is minor, the chore interferes with daily life.
Analytical Chemistry
May 28, 2010
0
0
Semaglutide is part of the glucagon-like peptide-1 (GLP-1) receptor targeting family of peptide drugs which are mainly used to treat diabetes but are difficult and expensive to make.
Biochemistry
Mar 12, 2024
0
68
Monitoring glucose levels is one of the key elements in health monitoring. A research team from the University of California, Berkeley, has now developed a battery-independent fluorescent nanosensor based on single-wall carbon ...
Bio & Medicine
Jan 2, 2024
0
39
Blood tests are a common, yet often painful, step in health care. But what if we could skip the needles altogether? Saliva and blood contain many of the same biomarkers, and collecting spit is as simple as drooling into a ...
Biochemistry
Nov 29, 2023
0
1
Scientists at the University of California, Davis, in partnership with the Mars Advanced Research Institute, have announced a significant breakthrough in the production of low-calorie sugar substitutes, such as allulose. ...
Biochemistry
Oct 24, 2023
0
132
Although diabetes is a common condition, no cure exists yet. Current therapies can manage blood sugar levels, but they do not address insulin resistance. But now, recent research reported in ACS Nano shows that targeting ...
Bio & Medicine
May 17, 2023
0
41
Blood sugar concentration, or glucose level, refers to the amount of glucose present in the blood of a human or animal. Normally, in mammals the blood glucose level is maintained at a reference range between about 3.6 and 5.8 mM (mmol/l). It is tightly regulated as a part of metabolic homeostasis.
Mean normal blood glucose levels in humans are about 90 mg/100ml, equivalent to 5mM (mmol/l) (since the molecular weight of glucose, C6H12O6, is about 180 g/mol). The total amount of glucose normally in circulating human blood is therefore about 3.3 to 7g (assuming an ordinary adult blood volume of 5 litres, plausible for an average adult male). Glucose levels rise after meals for an hour or two by a few grams and are usually lowest in the morning, before the first meal of the day. Transported via the bloodstream from the intestines or liver to body cells, Glucose is the primary source of energy for body's cells, fats and oils (ie, lipids) being primarily a compact energy store.
Failure to maintain blood glucose in the normal range leads to conditions of persistently high (hyperglycemia) or low (hypoglycemia) blood sugar. Diabetes mellitus, characterized by persistent hyperglycemia from any of several causes, is the most prominent disease related to failure of blood sugar regulation.
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