Diagnostic tools using synthetic biology

(Phys.org)—Synthetic biology is a multi-disciplinary field that applies engineering techniques to biological systems. While the foundations of synthetic biology were laid in the 1990s with the burgeoning of genomics and ...

Artificial intelligence detects the presence of viruses

Many biosensing applications rely on characterization of specific analytes such as proteins, viruses and bacteria, among many other targets, which can be accomplished by using micro- or nano-scale particles. In such biosensors, ...

New patch boosts brightness in medical diagnostic tests

Fluorescence-based biosensing and bioimaging technologies are widely used in research and clinical settings to detect and image various biological species of interest. While fluorescence-based detection and imaging techniques ...

Designing diamonds for medical imaging technologies

Japanese researchers have optimized the design of laboratory-grown, synthetic diamonds. This brings the new technology one step closer to enhancing biosensing applications, such as magnetic brain imaging. The advantages of ...

Research team develops a cocaine biosensor inspired from nature

Since the beginning of time, living organisms have developed ingenious mechanisms to monitor their environment. As part of an international study, a team of researchers has adapted some of these natural mechanisms to detect ...

page 1 from 2

Biosensor

A biosensor is an analytical device for the detection of an analyte that combines a biological component with a physicochemical detector component.

It consists of 3 parts:

A common example of a commercial biosensor is the blood glucose biosensor, which uses the enzyme glucose oxidase to break blood glucose down. In doing so it first oxidizes glucose and uses two electrons to reduce the FAD (a component of the enzyme) to FADH2. This in turn is oxidized by the electrode (accepting two electrons from the electrode) in a number of steps. The resulting current is a measure of the concentration of glucose. In this case, the electrode is the transducer and the enzyme is the biologically active component.

Recently, arrays of many different detector molecules have been applied in so called electronic nose devices, where the pattern of response from the detectors is used to fingerprint a substance.[citation needed]. In the Wasp Hound odor-detector, the mechanical element is a video camera and the biological element is five parasitic wasps who have been conditioned to swarm in response to the presence of a specific chemical. Current commercial electronic noses, however, do not use biological elements.

A canary in a cage, as used by miners to warn of gas, could be considered a biosensor. Many of today's biosensor applications are similar, in that they use organisms which respond to toxic substances at a much lower concentrations than humans can detect to warn of the presence of the toxin. Such devices can be used in environmental monitoring, trace gas detection and in water treatment facilities.

This text uses material from Wikipedia, licensed under CC BY-SA