An easier way of sneaking antibodies into cells

For almost any conceivable protein, corresponding antibodies can be developed to block it from binding or changing shape, which ultimately prevents it from carrying out its normal function. As such, scientists have looked ...

Cell chemistry illuminated by laser light

Raman microspectroscopy is a laboratory technique to produce molecular fingerprints of materials and biological specimens. However, to date fluorescence has interfered with effective application of this technique and limited ...

Elusive cancer-related protein captured in flight

Scientists have for the first time seen how the MYC protein, which plays a central role in cancer, binds to a key protein and controls important functions in the cell. The study, published in Nature Structural and Molecular ...

Study tracks evolutionary history of metabolic networks

By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks—which drive every cellular process from protein ...

Dynamic images show rhomboid protease in action

Rhomboid proteases are clinically relevant membrane proteins that play a key role in various diseases. Using solid-state NMR spectroscopy, researchers from Berlin's Leibniz-Forschungsinstitut für Molekulare Pharmakologie ...

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