It takes a(n academic) village to determine an enzyme's function

Scientists have sequenced the genomes of nearly 6,900 organisms, but they know the functions of only about half of the protein-coding genes thus far discovered. Now a multidisciplinary effort involving 15 scientists from ...

RNA folding: A little cooperation goes a long way

(Phys.org)—The nucleic acid RNA is an essential part of the critical process by which the cells in our bodies manufacture proteins. But noncoding RNAs also exist whose sequences, while not converted into proteins, play ...

Making sense of misfolded proteins

The endoplasmic reticulum of cells provides a pivotal quality-control system that eliminates improperly folded, or misfolded, glycoproteins, such as antibodies and hormones. The UDP-glucose:glycoprotein glycotransferase (UGGT) ...

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