Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic protein Nkx6.1 – a beta-cell enriched transcription factor – is ...
Cell & Microbiology
Sep 12, 2013
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Scientists once thought that neurons, or possibly heart cells, were the oldest cells in the body. Now, Salk Institute researchers have discovered that the mouse brain, liver and pancreas contain populations of cells and proteins ...
Cell & Microbiology
Jun 6, 2019
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274
A protein called "fascin" appears to play a critical transformation role in TGF beta mediated tumor metastasis, say researchers at Moffitt Cancer Center in Tampa, Fla., who published a study in a recent issue of the Journal ...
Biochemistry
Nov 9, 2011
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Using somatic cell nuclear transfer, a team of scientists led by Dr. Dieter Egli at the New York Stem Cell Foundation (NYSCF) Research Institute and Dr. Mark Sauer at Columbia University Medical Center has created the first ...
Cell & Microbiology
Apr 28, 2014
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For decades, researchers have tried to duplicate the function of beta cells, the tiny insulin-producing entities that don't work properly in patients with diabetes. Insulin injections provide painful and often imperfect substitutes. ...
Materials Science
Mar 14, 2016
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258
Notch – the protein that can help determine cell fate – maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein – TGF beta (transforming growth factor ...
Cell & Microbiology
Nov 1, 2012
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Two new papers in the Journal of General Physiology demonstrate the successes of using bifurcation theory and dynamical systems approaches to solve biological puzzles.
Cell & Microbiology
Jun 27, 2011
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The Wnt/β-catenin signaling pathway and microRNA 335 are instrumental in helping form differentiated progenitor cells from stem cells. These are organized in germ layers and are thus the origin of different tissue types, ...
Cell & Microbiology
Jan 23, 2014
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Synthetic biology offers a vision for the future of medicine, where cells could be re-engineered to fight diseases such as cancer and diabetes. For this to happen, scientists use viruses to infect and transfer new properties ...
Biotechnology
Mar 28, 2018
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49
The death of insulin-producing beta cells in the pancreas is a core defect in diabetes. Scientists in Italy and Texas now have discovered a new way that these cells die — by toxic imbalance of a molecule secreted by ...
Biochemistry
Feb 25, 2011
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