Examining the genesis of CRISPR's molecular scissors
Genome engineering may be the future of medicine, but it relies on evolutionary advances made billions of years ago in primordial bacteria, the original masters of gene editing.
Genome engineering may be the future of medicine, but it relies on evolutionary advances made billions of years ago in primordial bacteria, the original masters of gene editing.
Evolution
Sep 27, 2023
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38
Australian researchers have uncovered new genetic insights into Staphylococcus aureus, revealing what makes the bacterium so dangerous when it enters the blood.
Cell & Microbiology
Sep 12, 2023
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171
Signal transduction and perception regulates biological activities to adapt to changing environments. The Pert-Arnt-Sim domains are commonly available sensors found across diverse receptors in bacteria, eukaryotes, and archaea. ...
In a new study, researchers from the Faculty of Science of Charles University, in collaboration with researchers from Max-Planck Institute for Terrestrial Microbiology and European Molecular Biology Laboratory from Heidelberg, ...
Ecology
Aug 28, 2023
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46
For decades, the Y chromosome—one of the two human sex chromosomes—has been notoriously challenging for the genomics community to sequence due to the complexity of its structure.
Molecular & Computational biology
Aug 23, 2023
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1417
A group of genomic researchers at the Center for Genomic Sciences, in Mexico, working with a colleague from the Institute of Biotechnology, also in Mexico, has found a type of bacteria that might be the closest modern relative ...
In a study published in Cell, scientists from the National University of Singapore (NUS) and Imperial College London have discovered a new way by which bacteria transmit their genes, enabling them to evolve much faster than ...
Cell & Microbiology
Aug 4, 2023
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85
A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes—organisms that ...
Biotechnology
Jun 28, 2023
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1695
The recognition of the phenomenon known as horizontal (or lateral) gene transfer (HGT/LGT) revolutionized our understanding of evolutionary mechanisms. Unlike the conventional vertical transmission of genes from parent to ...
Cell & Microbiology
Jun 16, 2023
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519
Antibiotics affect the composition and dynamics of the gut microbiome. Treatment with antibiotics not only leads to a loss of biodiversity of microorganisms, but also often favors the selection of resistant strains of bacteria. ...
Evolution
Jun 6, 2023
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371