Potassium hunting on protein factories

Groundbreaking research at the new long-wavelength macromolecular crystallography beamline (I23) at Diamond Light Source has for the first time demonstrated the location of potassium ions in bacterial ribosomes. Ribosomes ...

Teaching antibiotics to be more effective killers

Research from the University of Illinois at Chicago suggests bond duration, not bond tightness, may be the most important differentiator between antibiotics that kill bacteria and antibiotics that only stop bacterial growth.

Ribosome recycling as a drug target

Ludwig Maximilian University of Munich researchers have elucidated a mechanism that recycles bacterial ribosomes stalled on messenger RNAs that lack termination codons. The protein involved provides a potential target for ...

Protein synthesis, ATP unnecessary for bacterial spore germination

Spores of Bacillus bacteria can survive for years in a dormant state, and then germinate in minutes. But it has long been unclear whether germination required protein synthesis, or cellular energy packets, which are known ...

Making sure antibiotics work as they should

Researchers at ETH Zurich are decoding the structure of the large ribosomal subunit of the mitochondria at an atomic level, thereby providing insight into the molecular architecture of this ribosome with implications for ...

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