An arms race that plays out in a single genome

Biological arms races are commonplace in nature. Cheetahs, for example, have evolved a sleek body form that lends itself to rapid running, enabling them to feast upon similarly speedy gazelles, the fastest of which may evade ...

How pathogenic bacteria weather the slings and arrows of infection

Infectious diseases are a leading cause of global mortality. During an infection, bacteria experience many different stresses—some from the host itself, some from co-colonizing microbes and others from therapies employed ...

A molecular on/off switch for CRISPR

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas. At the center of this system is a surveillance ...

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