Antibody-drug conjugates (ADCs), a complex covalently linking a potent cytotoxin onto the antibody, has attracted great interest as a novel biotherapeutic approach. Site-specific conjugation of potent payloads can improve ...
Biochemistry
Feb 8, 2022
0
36
Chemotherapy works off of a basic premise: kill all rapidly-growing cells in an effort to wipe out tumor cells. The tactic, while generally effective, has quite a few off-target casualties, including cells that produce hair ...
Biochemistry
Aug 27, 2019
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169
A method to activate targeted drugs, or smart drugs, only at the selected site of action, an approach that improves the drug's therapeutic effect and minimizes side effects, has been developed in a study led by Georgia State ...
Materials Science
May 17, 2018
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154
Chemists at The Scripps Research Institute (TSRI) have devised a new technique for connecting drug molecules to antibodies to make advanced therapies.
Biochemistry
Oct 7, 2013
0
0
