Cheetahs' unrivaled speed explained by their 'sweet spot' size, study finds
A new Imperial College London study has answered a long-held question about why medium-sized land animals like cheetahs tend to be fastest.
A new Imperial College London study has answered a long-held question about why medium-sized land animals like cheetahs tend to be fastest.
Plants & Animals
Mar 12, 2024
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120
In the ever-evolving realm of microscopy, recent years have witnessed remarkable strides in both hardware and algorithms, propelling our ability to explore the infinitesimal wonders of life. However, the journey towards three-dimensional ...
Optics & Photonics
Feb 14, 2024
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71
In the animal kingdom, there are many grand examples of species that make sense of their world by expertly deciphering even weak signals from their surroundings.
Plants & Animals
Feb 2, 2024
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223
Cultivating seed mixtures for local pastures is an age-old method to produce cost-effective and balanced animal feed, enhancing agricultural autonomy and environmental friendliness in line with evolving European regulations ...
Molecular & Computational biology
Jan 18, 2024
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1
Repeated failures to reproduce make fruit flies stressed and frustrated, which in turn makes them less resilient to other types of stress, Julia Ryvkin at Bar-Ilan University and colleagues report in PLOS Genetics.
Plants & Animals
Jan 18, 2024
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5
Accurate quantification of multi-animal behavior plays a pivotal role in unraveling the intricacies of animal social interactions with far-reaching applications in neuroscience and ecology.
Ecology
Jan 9, 2024
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21
In a complex called chromatin, long strands of DNA in cells' nuclei are tightly wrapped around a scaffolding of proteins, like a rolled-up ball of yarn. A new study by Weill Cornell Medicine investigators reveals that beyond ...
Cell & Microbiology
Jan 2, 2024
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70
Ana Mateos and Jesús Rodríguez, scientists at the Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), have published a paper in the journal Palaeogeography, Palaeoclimatology, Palaeoecology showing that ...
Ecology
Nov 30, 2023
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16
Migration is a survival mechanism for many species. Animals travel to find food, reproduce, reduce competition, escape predators or escape winter.
Ecology
Nov 13, 2023
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14
University of Maryland researchers studied synaptic changes in an animal model before and after it developed vision, which plays a key role in circadian rhythm.
Biochemistry
Oct 27, 2023
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60
An animal model is a non-human animal that has a disease or injury that is similar to a human condition. These test conditions are often termed as animal models of disease. The use of animal models allows researchers to investigate disease states in ways which would be inaccessible in a human patient, performing procedures on the non-human animal that imply a level of harm that would not be considered ethical to inflict on a human.
In order to serve as a useful model, a modeled disease must be similar in etiology (mechanism of cause) and function to the human equivalent. Animal models are used to learn more about a disease, its diagnosis and its treatment. For instance, behavioral analogues of anxiety or pain in laboratory animals can be used to screen and test new drugs for the treatment of these conditions in humans. A 2000 study found that animal models predicted human toxicity in 71% of cases, with 63% for nonrodents alone and 43% for rodents alone.
Animal models of disease can be spontaneous (naturally occurring in animals), or be induced by physical, chemical or biological means. For example,
The increase in knowledge of the genomes of non-human primates and other mammals that are genetically close to humans is allowing the production of genetically engineered animal tissues, organs and even animal species which express human diseases, providing a more robust model of human diseases in an animal model.
Animal models observed in the sciences of psychology and sociology are often termed animal models of behavior.
In quantitative genetics, the term animal model is used to refer to statistical models in which phenotypic variance is compartmentalised into environmental, genetic and sometimes maternal effects. Such animal models are also known as "mixed models".
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